生物材料在预防运动损伤致肌腱粘连中的应用前景

Application prospect of biological materials to prevent tendon adhesion induced by sports injuries

背景:高科技生物材料具有良好的防肌腱粘连功能。目的:评价不同生物材料预防运动损伤修复后肌腱和腱鞘之间粘连的效果,寻找适合生物材料。方法:以"生物材料,运动,肌腱损伤、预防粘连"为中文关键词,以"biological material,sports,tendon injury,antistick"为英文关键词,采用计算机检索中国期刊全文数据库、PubMed数据库1990年1月至2011年3月相关文章。结果与结论:几丁糖、壳聚糖/聚乳酸聚乙醇酸共聚物乳化膜、透明质酸钠等高分子化合物胶体及药物薄膜等新型生物材料可有效预防运动肌腱损伤导致的肌腱粘连,各种材料均由优缺点,科学合理的综合运用多种药物或高科技生物材料预防肌腱损伤后粘连将是未来的发展方向。

BACKGROUND： High-tech biological materials can well prevent the adhesion between tendon and tendon sheath. OBJECTIVE： To evaluate the effects of different biological materials on preventing the adhesion between tendon and tendon sheath after the repair of sports injuries, and to search for suitable biological materials. METHODS： The keywords of ＂biological material, sports, tendon injury, antistick＂ were used in Chinese and English, respectively. A computer search of China Academic Journal Full-text database and PubMed database from January 1990 to March 2011 was performed. RESULTS AND CONCLUSION： The new-type biological materials such as chitosan, mechanisms of chitosan, chitosan/ poly tactic-co-glycolic acid film and sodium hyaluronate can prevent tendon adhesion induced by sports injuries effectively. However, all kinds of materials have their advantages and disadvantages, and therefore, the development direction in the future is to prevent tendon adhesion after sports injuries by reasonable use of various drugs or high-tech biological materials.