低剂量螺旋CT在矽肺诊断中的应用

Low-dose Spiral CT in the Diagnosis of Silicosis

目的探讨低剂量螺旋CT在矽肺诊断中的应用价值。资料与方法 60例矽肺患者分别采用螺旋CT常规剂量(130mA)、低剂量(20mA)进行扫描,比较两种扫描条件下矽肺阴影大小、密集度及矽肺分期情况。结果 20mA与130mA螺旋CT扫描均显示≥20mm阴影16例,大阴影5例,小阴影39例。130mA扫描1级密集度35例,2级密集度10例,3级密集度15例;20mA扫描1级密集度33例,2级密集度12例,3级密集度15例。20mA与130mA螺旋CT扫描均显示矽肺Ⅰ期26例,Ⅱ期12例,Ⅲ期22例,两者在显示矽肺阴影大小、密集度以及矽肺分期方面差异均无统计学意义(P>0.05)。结论 20mA低剂量与130mA常规剂量螺旋CT扫描在显示矽肺阴影大小、密集度以及矽肺分期方面无显著差异,20mA低剂量螺旋CT扫描可作为矽肺筛查的手段之一在临床应用。

Purpose To explore the value of low-dose spiral CT in the diagnosis of silicosis. Materials and Methods Sixty patients with silicosis were scanned with spiral CT using routine dose of 130 mA and low dose of 20 mA, respectively. The shadow size, intensity and the stage of silicosis under two scanning parameters were compared. Results There were 16 cases with ≥ 20 mm shadows, 5 cases with large shadows and 39 cases with small shadows on both 20 mA and 130 mA scanning. Silicosis intensity was level 1 in 35 cases, level 2 in 10 cases, and level 3 in 15 cases with 130 mA scan, compared with level 1 in 33 cases, level 2 in 12 cases, and level 3 in 15 cases with 20 mA scan. Both 20 mA and 130 mA scans diagnosed 26 cases of stage Ⅰ, 12 of stage Ⅱ, and 22 of stage Ⅲ. There was no statistical difference in shadow size, intensity and staging of silicosis （P0.05）. Conclusion 20 mA low-dose spiral CT has no statistical difference in display shadow size, intensity and staging of silicosis, thus it can be applied in screening of silicosis.