中西医结合治疗银屑病关节炎的临床研究

Clinical Research of Psoriatic Arthritis Treated by the Integration of Traditional Chinese Medicine and Western Medicine

目的:探讨中西医结合治疗银屑病关节炎的临床疗效。方法:将45例患者随机分为两组,对照组采用甲氨蝶呤(MTX)+环孢菌素(CS)+非甾体类抗炎药治疗;治疗组在对照组治疗的基础上采用四妙勇安汤加味(方药组成:金银花30 g,当归20 g,玄参20 g,生地黄12 g,虎杖12 g,白花蛇舌草20 g,山慈菇10 g,鹿衔草10 g,甘草15 g)治疗。结果:对照组有效率为44.4%,治疗组有效率为88.9%,两组有效率比较,差异有统计学意义(P<0.05)。结论:中西医结合治疗银屑病关节炎的临床疗效显著。

Objective ：To discuss the clinical curative effects of psoriatic arthritis treated by the integration of traditional Chinese medicine and western medicine. Methods ：45 cases of psoriatic arthritis patients suited for the inclusive standard were randomly divided into two groups, the control group adopted combination drug therapy, namely, Methotrexate （MTX） plus Cyclosporin （CS） plus non-steroidal anti-in-flammatory drugs ; the treatment group was treated by addition of Simiao Yongan Decoction （ composition ： Lonicera japonica Thunb 30 g, Angelica sinensis 20 g, Scrophularia ningpoensis Hemsl 20 g, Rehmannia glutinosa 12 g, Rhiaoma Polygoni Cuspidati 12 g, Herba Hedyotis Diffusae 20 g, Cremastra appendiculata 10 g, Pyrola deco-rata 10 g, Radix Glycyrrhizae 15 g） based on the control group therapy. Resuhs：The effective rate in the control group and the treatment group was 44.4% and 88.9% respectively, and the difference between them had statistical significance（ P 〈 0.05 ）. Conclusion：Clinical curative effect of psoriatic arthritis treated by the integration of traditional Chinese medicine and western medicine is obviously superior to the treatment of simple western medicine.