摘要
One new and 16 known compounds were isolated from Abies sibirica. Their structures were assigned mainly on the basis of NMR and MS spectroscopic data. In bioassay for anti-proliferative activity against four human tumor cells, compound 7 exhibited selective anti-proliferative activity against COLO-205 tumor cell with an IC50 value of 0.9 μg/mL.
One new and 16 known compounds were isolated from Abies sibirica. Their structures were assigned mainly on the basis of NMR and MS spectroscopic data. In bioassay for anti-proliferative activity against four human tumor cells, compound 7 exhibited selective anti-proliferative activity against COLO-205 tumor cell with an IC50 value of 0.9 μg/mL.
基金
supported by program NCET Foundation
NSFC(No.30725045)
partially supported by Global Research Network for Medicinal Plants(GRNMP)
King Saud University,Shanghai Leading Academic Discipline Project(No.B906),FP7- PEOPLE-IRSES-2008(TCMCANCER Project 230232)
Key Laboratory of Drug Research for Special Environments,PLA,Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products(No.10DZ2251300)
the Scientific Foundation of Shanghai China(No.09DZ1975700,09DZ1971500, 10DZ1971700)
the Twelfth Five-Year National Science & Technology Support Program(No.2012BAI29B06)
