呼吸机辅助呼吸治疗脑干出血并发呼吸衰竭疗效观察

Clinical effect of the application of mechanical ventilation in bralnstem hemorrhage complicated with respira- tory failure

目的观察呼吸机辅助呼吸治疗脑干出血并发呼吸衰竭的临床疗效。方法回顾性分析29例脑干出血并发呼吸衰竭患者的临床资料，在给予常规对症治疗的基础上，予以呼吸机辅助呼吸治疗，分析呼吸机辅助治疗前后呼吸指标的变化。结果治疗后，29例患者中好转出院11例（37．9％），自动出院10例（34．5％），死亡8例（27．5％）；呼吸频率、氧分压、二氧化碳分压、血氧饱和度等均较治疗前明显改善（t=4．932、4．393、3．784、3．297，均P〈0．05）；血浆白蛋白水平、Glasgow评分等均较治疗前明显改善（t=2．675、4．947，均P〈0．05），治疗前后血糖水平、外周血白细胞计数差异均无统计学意义（t=1．037、0．852，均P〉0．05）。结论采用呼吸机辅助呼吸治疗脑干出血并发呼吸衰竭能显著改善各项呼吸指标，提高患者的生存率。

Objective To observe the clinical efficacy of ventilator-assisted breathing for the treatment of respiratory failure brainstem hemorrhage. Methods Clinical data of 29 cases of brainstem hemorrhage complicated with respiratory failure were retrospectively analyzed. Patients were treated with conventional symptomatic treatment based on ventilator-assisted breathing therapy and before and after treatment of ventilator-assisted breathing index changes were analyzed. Results After treatment, 29 patients improved and discharged 11 patients （ 37.9% ）, and automatically discharged 10 patients （ 34.5 % ）, 8 patients died （27.5 % ） ; R, Pa02, PaC02, Sa02 significantly improved than before treatment （t = 4.932,4. 393,3. 784,3. 297, all P 〈 0.05 ） ;compared with pre-treatment plasma ＇albumin level, Glasgow score improved significantly （ t = 2. 675,4. 947, all P 〈 0.05 ）, blood glucose level before and after treatment, peripheral blood leukocytes count had no statistically significant differences （ t = 1. 037,0. 852, all P 〉 0.05 ）. Conclusion Ventilator-assisted respiratory therapy brainstem hemorrhage complicated with respiratory failure can significantly improve various respiratory indicators, improve the survival rate.