自拟中药方剂治疗儿童手足口病疗效观察

Efficacy research of self-made traditional Chinese medicine for hand-foot-mouth disease

目的探讨自拟中药方剂治疗儿童手足口病的临床疗效。方法118例手足口病患儿随机平均分为两组，对照组（；9例）给予常规西药治疗，观察组（59例）在此基础上给予自拟中药方剂治疗。观察比较两组的临床疗效。结果经治疗，观察组发热消退时间（2．0±0．7）d、皮疹消退时间为（3．9±0．9）d、住院时间为（3．5±1．3）d，均明显短于对照组的（3．6±1．3）d、（5．9±1．6）d、（5．7±1．4）d（t=3．21、3．81、4．02，均P〈0．05）；观察组治疗总有效率为94．9％，明显高于对照组的81．4％（X^2=4．02，P〈0．05）。结论自拟中药方剂治疗儿童手足口病疗效确切、安全，值得临床推广应用。

Objective To explore clinical effect of self-made traditional Chinese medicine for hand-foot- mouth disease. Methods 118 cases with hand-foot-mouth disease were randomly divided into two groups. The control group （ n = 59 ） were treated by regular western medicines. On that basis, the study group （ n = 59 ） were treated bys elf-made traditional Chinese medicine. And the curative effects of two groups were observed. Results Fever subsidise time of the study group after treatment was （2.0 ±0.7 ） d, which was significantly shorter than that of the control group, with P 〈0.05. Rash subsidise time of the study group after treatment was （ 3.9±0.9 ） d, was significantly shorter than that of the control group, with P 〈 O. 05. Length of hospital stay of the study group after treatment was （3.5 ±1.3 ） d, was significantly shorter than that of the control group, with P 〈0. 05. Total effective rate of the study group after treatment was 94.9% ,which was significantly higher than that of the control group （81.4%）,with P 〈 0.05. Conclusion Self-made traditional Chinese medicine for hand-foot-mouth disease has good clinical curative effect, has high security and reliability.