摘要
目的探讨步长脑心通在短暂性脑缺血发作二级预防中对D‐二聚体和血清溶血磷脂酸(lysophosphatidic acid,LPA)的影响。方法回顾我院2006年5月至2011年5月收治的短暂性脑缺血发作患者42例。入院后,随机分为2组:步长脑心通组(A组)、阿司匹林组(B组),比较分析2组治疗前后D‐二聚体和血清溶血磷脂酸表达。结果治疗后,A组D‐二聚体、血清溶血磷脂酸和B组比较,没有统计学意义(P>0.05),A组的副反应和B组比较有统计学意义(P<0.05)。结论步长脑心通在短暂性脑缺血发作二级预防中具有一定的优势,可能与抑制D‐二聚体和血清溶血磷脂酸有关。
【Objective】 To investigate the effect of buchang naoxintong capsules on expression of D-dimers and lysophosphatidic acid in secondary prevention of transient ischemic attack.【Methods】 Retrospectively analyze 42 cases with transient ischemic attack from May 2006 to May 2011 in our hospital.They were randomLy divided into two groups,buchang naoxintong capsules group,Aspirin group,The expression of D-dimers and the lysophosphatidic acid were evaluated before and after treatment.【Resluts】After treatment,the expression of D-dimers and lysophosphatidic acid of A group was no significantly difference with B group,（p0.05）.Compared with Aspirin group,the complications of buchang naoxintong capsules group was significantly lower,and the difference was statistically significant（p0.05）.【Conclusion】buchang naoxintong capsules in the treatment secondary prevention of transient ischemic attack compared with Aspirin has certain advantages,it was possibly through decreasing the expression of D-dimers and lysophosphatidic acid
出处
《中国医学工程》
2012年第9期22-23,25,共3页
China Medical Engineering
