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乙型肝炎病毒标志物模式及病毒DNA定量与原发性肝癌临床相关性研究 被引量:8

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摘要 目的探讨原发性肝癌与乙肝病毒标志物模式及病毒定量之间的关系。方法选择诊断明确的248例原发性肝癌患者,对其乙肝病毒标志物各项及其组成模式,HBV-DNA AFP进行统计分析。结果248原发性肝癌例HBsAg阳性率为90.32%(224/248),HBsAg(+)、HBeAb(+)、HBcAb(+)组(小三阳)148例,所占比例59.67%(148/248),小三阳患者血清HBV-DNA检出率为51.35%(76/148),HBV-DNA平均拷贝数为(104.58±2.17)copy/ml。HBsAg、HBeAg、HBcAb(俗称"大三阳")阳性率为20.96%(52/248),大三阳患者的HBV-DNA阳性率为92.30%(48/52),HBV DNA平均拷贝数为(107.11±1.72)copy/ml。结论原发性肝癌患者乙型肝炎病毒感染阳性率高,小三阳病毒模式是肝癌的危险因素,积极预防和控制H BV感染是减少原发性肝癌发生的关键。
出处 《江西医药》 CAS 2012年第10期888-889,共2页 Jiangxi Medical Journal
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