拉萨地区新生儿红细胞增多症临床研究

Clinical research of neonatal polycythemia in Lhasa area

目的回顾性分析高海拔地区新生儿缺氧与红细胞增多症的关系,针对高原世居藏族新生儿与移居高原汉族新生儿红细胞增多症临床特点进行研究。方法选取2005年1月至2006年10月新生儿红细胞增多症40例(其中藏族20例,汉族20例)进行了临床经皮血氧饱和度(TcSpO2),外周血常规研究分析。结果汉族新生儿血红蛋白(Hbg)、血细胞比容(Hct)、红细胞(RBC)三项值明显高于藏族新生儿,差异有统计学意义(P<0.05)。结论 40例临床分析结果显示,高原地区汉族新生儿红细胞增多症患儿临床表现较藏族新生儿重,以心肌受损和脑部受损为主要表现,因此在高原地区新生儿红细胞增多症患儿应引起临床医护人员的高度重视,尤其是汉族新生儿,应早期积极进行干预治疗。

Objective To retrospectively analyse the relationship between the neonatal hypoxia and polycythemia in the high altitude area,and to study the clinical characteristics of the native Tibetans newborns and the emigrated plateau Han neonates.Methods 40 cases of neonatal polycythemia including Tibetan 20 cases and Han 20 cases were collectd from January 2005 to October 2006 and performed the clinical research on transcutaneous oxygen satuation（TcSpO2）and peripheral blood routine.Results Hgb,Hct and RBC of Han neonates were significantly higher than those of Tibetan newbrons with statistical difference（P0.05）.Conclusion The clinical manifestations of neonatal polycythemia in Han neonates are more severe than those of Tibetan newborns.The main manifestations are myocardial damage and brain damage.Therefore,neonatal polycythemia in the high altitude area,especially Han neonates,should arouse the medical staff to pay great attention to and should be conducted the active intervention at early stage.