咪唑斯汀联合赛庚啶治疗湿疹的临床疗效观察

Clinical observation on mizolastine combined with cyproheptadine to treat eczema

目的探讨咪唑斯汀与赛庚啶在湿疹患者中的联合应用价值。方法选取我院收治的湿疹患者38例,随机分为观察组和对照组,每组各19例。两组湿疹者经明确诊断后,均给予赛庚啶的药物治疗,观察组患者则在此基础之上加用咪唑斯汀的药物联合治疗,并分别对两组湿疹患者的临床治疗情况和不良反应发生情况进行比较和分析。结果观察组患者与对照组患者相比,其痊愈率和总有效率均明显提高,差别均具有统计学意义(P<0.05);其不良反应发生率有所降低,但不具有统计学意义(P>0.05)。结论咪唑斯汀联合赛庚啶治疗湿疹,其疗效显著且毒副反应小。

Objective To probe into the combined value for eczema patients with mizolastine combined with cyproheptadine.Methods Selected 38 eczema patients in our hospital.All the patients divided into observation group and the control group randomly,there were 19 cases in each group.All the eczema patients were treated by a clear diagnosis and treated with cyproheptadine,while patients in observation group treated with combination therapy by mizolastine.Compared and analyzed the clinical treatment and adverse reactions occurred of eczema patients in two groups.Results Compared with control group,patients in observation group the cure rate and total efficiency were significantly improved,there were statistically significant(P<0.05).At the same time,the incidence of adverse reactions of the observation group was decreased,but there were no statistically significant(P>0.05).Conclusions Mizolastine combined with cyproheptadine in the treatment of eczema is significant efficacy and toxicity.