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糖皮质激素在儿童危重症手足口病中的应用 被引量:11

Application of Glucocorticoid in Severe Hand-foot-and-Mouth Disease in Children
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摘要 目的分析2011年本院收治的重症手足口病(HFMD)患者的临床特点、治疗情况,观察应用糖皮质激素的效果。方法将56例重症HFMD患儿随机双盲分为激素治疗组与非激素治疗组,2组病例均采用抗病毒、对症综合治疗,激素治疗组在此治疗基础上加用激素。结果 2组痊愈出院49例,遗留肢体活动障碍3例。其中激素治疗组1例,非激素治疗组2例;激素治疗组死亡1例。2组疗效比较无明显差异。结论重症HFMD患者应用糖皮质激素冲击疗法的效果并不显著。
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2012年第22期1768-1769,共2页 Journal of Applied Clinical Pediatrics
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  • 1胡晋怀,胡晓峰.手足口病患儿血清心肌酶谱检测及临床意义[J].医学检验与临床,2008,20(1):44-45. 被引量:34
  • 2Ho M, Chen ER, Hsu KH, et al. An epidemic of enterovirus 71 infection in Taiwan. Taiwan Euterovirus Epidemic-Working Group. N Engl J Med, 1999, 341:929-935.
  • 3Chang LY, Hsia SH, Wu CT, et al. Outcome of enterovirus 71 infections with or without stage-based management: 1998 to 2002. Pediatr Infect Dis J, 2004, 23:327-332.
  • 4Chan LG, Parashar UD, Lye MS, et al. Deaths of children during an outbreak of hand, foot, and mouth disease in sarawak, malaysia: clinical and pathological characteristics of the disease. For the Outbreak Study Group. Clin Infect Dis, 2000,31:678- 683.
  • 5Lin TY, Chang LY, Huang YC, et al. Different prointlammatory reactions in fatal and non-fatal enteroviras 71 infections: implications for early recognition and therapy. Acta Paediatr, 2002,91:632-635.
  • 6Chart KP, Goh KT, Chong CY, et al. Epidemic hand, foot and mouth disease caused by human enterovirus 71, Singapore. Emerg Infect Dis, 2003, 9:78-85.
  • 7Chang LY, King CC, Hsu KH, et al. Risk factors of enterovirus 71 infection and associated hand, foot, and mouth disease/ herpangina in children during an epidemic in Taiwan. Pediatrics, 2002,109 : e88.
  • 8Yang TT, Huang LM, Lu CY,et al. Clinical features and factors of unfavorable outcomes for non polio enterovirus infection of the central nervous system in northern Taiwan, 1994-2003[J]. Journal of,Microbiology Infect,2005,38(6) :417- 242.
  • 9Shih SR, Li YS, Chiou CC, et al. Expression of capsid [correction of caspid] protein VP1 for use as antigen for the diagnosis of enterovirus 71 infection[J]. J Med Virol, 2000,61(2):228-234.
  • 10Brown BA, Oberste MS, Alexander JP, et al. Molecular epidemiology and evolution of enterovirus 71 strains isolated from 1970 to 1998[J]. J Virol, 1997,73(12):9969- 9975.

共引文献261

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  • 1胡雁.正确认识循证护理 推动护理实践发展[J].中华护理杂志,2005,40(9):714-717. 被引量:283
  • 2卫生部办公厅.手足口病诊疗指南(2010年版)[EB/OL].http://www.swww.com.cn/notice/shouzuhou2010.doc.
  • 3中华人民共和国卫生部.手足口病诊疗指南(2010年版)[S].2010.
  • 4中华人民共和国卫生部.肠道病毒71型(EV71)感染重症病例临床救治专家共识(2011年版)[S].2011-05-13.
  • 5中华人民共和国卫生部.手足口病诊疗指南(2010年版).[S/OL].(2010-04-21).http://www.moh.gov.cn/publicfiles/business/htmlfiles/mohyzs/s3586/201004/46884.htm.
  • 6卫生部疾病预防控制局.手足口病防治指南[EB/OL].2007(2007-05-24)[2011-11-23].
  • 7潘家华,练名武,陈永龙,等.重症手足口病高危因素lo-gistic回归分析[C].中华医学会第十六届全国儿科大会论文汇编.昆明:中华医学会儿科学分会,2011:213.
  • 8Ooi MH,Wong SC,Lewthwaite P,et al.Clinical features,diagnosis,and management of enterovirus 71[J].Lancet Neurol,2010,9 (11):1097-1099.
  • 9Lee TC,Guo HR,Su H J,et al.Diseases Caused by Enterovirus 71 Infection[J].Pediatr Infect Dis J,2009,28(10):904-910.
  • 10Lin TY,Chang LY,Hsia SH,et al.The 1998 enterovirus 71 outbreak in Taiwan:pathogenesis and management[J].Clin Infect Dis,2002,34:S52-57.

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