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肺炎克雷伯菌ESBLs的检测及多重耐药性分析 被引量:8

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摘要 目的分析肺炎克雷伯菌的多重耐药性、产ESBLs情况、标本来源、临床科室的分布和年龄的分布情况。方法运用全自动微生物分析仪鉴定细菌,采用琼脂稀释法测定最小抑菌浓度;采用双纸片协同法检测超广谱β-内酰胺酶(ESBLs);用χ2检验分析数据。结果共分离158株肺炎克雷伯菌,其中多重耐药菌占89.24%,对阿米卡星的耐药率最低(36.08%);ESBLs的检出率为34.81%,头孢他啶、阿米卡星、左氧氟沙星、复方新诺明在ESBLs阳性组与阴性组的耐药率差异有统计学意义;标本的最主要来源为痰液(63.92%);标本、ESBLs和多重耐药菌的检出率(31.65%、48.00%、100.00%)都是危重医学科最高;感染者以老年人为主(51.27%)。结论多重耐药和产ESBLs的肺炎克雷伯菌常见,ESBLs与肺炎克雷伯菌的耐药性关系密切。
出处 《重庆医学》 CAS CSCD 北大核心 2012年第33期3525-3528,共4页 Chongqing medicine
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二级参考文献22

共引文献37

同被引文献98

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