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MMP-9及其相关因子与宫颈癌 被引量:7

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摘要 宫颈癌是全球女性常见的恶性肿瘤之一,其占女性新增癌症患者的9%(529 800),癌症死亡总数的8%(275 100)[1]。宫颈癌晚期死亡的主要原因之一就是癌细胞的浸润和转移。肿瘤细胞侵袭和转移的步骤之一是对细胞外基质(extracellular matrix,ECM)的降解,而ECM降解的关键酶是基质金属蛋白酶(matrix metalloproteinase,MMP)。
作者 李婵玉 李力
出处 《重庆医学》 CAS CSCD 北大核心 2012年第33期3545-3547,共3页 Chongqing medicine
基金 第三军医大学校管课题(2007xg063)
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  • 2赵建农,王翦,刘运生,王宇田,聂新民.PTTG、bFGF和MMP-9的表达与垂体腺瘤侵袭性的关系[J].中华神经医学杂志,2007,6(3):282-285. 被引量:4
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