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强化他汀类药物对老年冠心病患者择期介入治疗后造影剂肾病的预防作用 被引量：8

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摘要 造影剂肾病（contrastinducednephropathy，CIN）是冠状动脉介入诊疗后的一种常见并发症，是指排除其他影响肾功能的原因，应用造影剂48～72h后血清肌酐较原有基础水平升高25％或者绝对值升高44．2μmol／L以上。老年冠心病患者肾脏储备及代偿功能差，且常合并多种疾病，极易发生CIN。因此，寻求有效预防老年冠心病患者CIN发生的措施显得尤为重要。他汀类药物因其抗炎症、抗氧化、保护内皮功能等多重生物效应而对肾功能具有一定的保护作用，但是否能预防CIN的发生、合适的剂量及机制，
作者 乔英 周小雨 李珊珊 李英 杨世诚 刘园园 刘晓罡 陈永利 付乃宽
机构地区 天津医科大学研究生院 天津市胸科医院心内一科
出处 《中华老年心脑血管病杂志》 CAS 北大核心 2012年第12期1325-1326,共2页 Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
基金 天津市卫生局攻关基金(10KG122)
关键词 老年冠心病患者 造影剂肾病 他汀类药物 预防作用 介入治疗后 冠状动脉介入诊疗 择期 保护作用
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献9

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二级参考文献45

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共引文献34

同被引文献111

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引证文献8

二级引证文献59

中华老年心脑血管病杂志
2012年 第12期

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