摘要
【方法】通过正交优化法得到30%戊唑醇·甲基硫菌灵水悬浮剂的最佳配方。【结果】戊唑醇原药20%,甲基硫菌灵10%,D10024.5%,农乳33#2.5%,乙二醇5%,黄原胶0.25%,有机硅消泡剂0.3%,蒸馏水补足至100%。加工工艺研究发现:使用立式砂磨机,转速1400r/min,锆珠(d=1.2mm)最佳用量(即是制剂质量(埘)的1.9倍,最佳研磨时间为1.5h。【结论】得到的悬浮剂在pH值6.45—6.50条件下,(54±2)℃热贮14d,无析水、分层现象,分解率〈1%,倾倒性合格,产品各项指标符合悬浮剂的要求。
[Methods] Through the orthogonal optimization method, the formulation of tebuconazole, thiophanate- methyl 30% SC was obtained. [Results] The composition consisted of tebuconazole 20%, thiophanate-methyl 10%, D1002 4.5%, Nongru 33# 2.5%, ethanediol 5%, xanthan gum 0.25%, organic silicon defoamer 0.3%, the other component was distilled water. Vertical sanding machine was used to produce the formulation at 1400 r/min, the optimized milling time fixed on 1.5 h. Numerically, the volume of zirconium bead (d=1.2 mm) was 1.9 times of the quality of the preparation. [Conclusions] At the pH value of 6.45-6.50, the formulation had been stored at the temperature 54±2)℃ for 14 days, the decompositionratio was 〈1%, there were not precipitation and stratification, and it had good pourability, which conformed to the requirements for the formulation.
出处
《农药》
CAS
北大核心
2012年第12期878-880,883,共4页
Agrochemicals
基金
山东省自然科学基金(ZR2012CQ015)
关键词
戊唑醇
甲基硫菌灵
配方筛选
工艺优化
tebuconazole
thiophanate-methyl
formulation selection
process optimization