复方亚甲蓝液用于肛周术后镇痛的效果观察

Clinical Observation on Postoperative Analgesic Effects of Compound Methylene Blue Solution for Perianal Pain

为探讨复方亚甲蓝液在肛周术后镇痛的效果，将840例肛周手术患者随机分为治疗组和对照组，每组420例，对照组采用保留齿状线肛周常规手术治疗，治疗组在对照组手术的基础上加行复方亚甲蓝液切缘封闭注射。观察两组术后疼痛程度、舒适度、创口水肿等情况。结果显示，在疼痛程度、舒适度、创口水肿等方面，治疗组明显优于对照组（P〈0．05）。结果表明，在肛周手术后加行复方亚甲蓝液切缘封闭注射，可以明显减少术后并发症的发生，减轻患者痛苦，缩短创面愈合时间。

In order to discuss the postoperative analgesic effects of compound methylene blue solution on perianal pain,840 patients with perianal diseases were randomly divided into treatment group and control group,420 patients for each. Conventional surgical treatment was given to control group with dental line being preserved, while additional compound methylene blue solution was injected into the resection margins in treatment group. Both groups were observed for severity of pain, comfortability, postoperative edema of wound margins and so on. The results showed that treatment group was superior to control group in severi- ty of pain, comfortability, postoperative edema of wound margins（ P d0.05）. It is concluded that additional injection of compound methylene blue solution into wound margins can obviously reduce the occurrence of complications, relieve patients suffering and shorten wound surface healing time.