反复自然流产患者血清ThAb、AsAb、EMAb和AoAb检测的临床意义

Clinical Significance of Determination of Changes of Serum ThAb,AsAb,EMAb and AoAb Levels in Patients with Recurrent Spontaneous Abortion

目的:探讨了反复自然流产患者血清ThAb、AsAb、EMAb和AoAb水平的变化及临床意义。方法:应用放射免疫分析和斑点免疫法对84例反复自然流产患者进行了血清ThAb、AsAb、EMAb和AoAb的检测,并与35名健康孕妇作比较。结果:反复自然流产患者血清ThAb、AsAb、EMAb和AoAb的阳性率显著地高于正常孕妇组(P<0.05)。结论:检测反复自然流产患者血清ThAb、AsAb、EMAb和AoAb水平的变化对疾病的诊断和发病机制有一定的临床价值。

Objective To explore the clinical significance of determination of changes of serum ThAb,AsAb,EMAb and AoAb levels in patients with recurrent spontaneous abortion.Methods Serum ThAb（with RIA）,serum AsAb,EMAb and AoAb（with spotting immune method） levels were detected in 84 cases with recurrent spontaneous abortion and 35 normal pregnancy women.Results Serum ThAb,AsAb,EMAb and AoAb levels were significantly higher than those in normal pregnancy women（P0.05）.Conclusion Determination of changes of serum ThAb,AsAb,EMAb and AoAb levels in patients with recurrent spontaneous abortion were helpful for outcome prediction and possess importance clinical values.