认知行为疗法联合度洛西汀治疗抑郁症躯体化症状疗效分析

Study on the curative effect of the Cognitive-behavioral therapy combined with Duloxetine in the treatment of depression with somatic disorder

【目的】研究认知行为疗法联合度洛西汀治疗抑郁症躯体化症状的疗效。【方法】将60例抑郁症躯体化症状患者根据就诊顺序随机分为研究组(度洛西汀与认知行为疗法联合应用治疗)和对照组(单用度洛西汀治疗),各30例,于治疗前和治疗后2、4、8、12周采用症状自评量表(SCL-90)各项因子及12周汉密顿抑郁量表(HAMD)的减分率评定疗效,不良反应症状量表(tess)来评价药物不良反应。【结果】治疗2、4、8、12周,研究组的躯体化、抑郁、焦虑等因子分与对照组比较有显著差异(P<0.05),研究组的显效率有效率均优于对照组,均有显著差异(P<0.05),两组的不良反应少且较轻微。【结论】认知行为疗法联合度洛西汀治疗抑郁症躯体化症状的疗效优于单纯药物治疗。

[Objective] Research cognitive behavioral therapy combined duloxetine treatment the curative effect of depression somatization symptoms. [ Methods] 60 patients with depression somatization symptoms patients according to the order of a randomly divided into study group （duloxetine and cognitive behavior therapy combined application treatment） and control group （use duloxetine treatment）, and each group was 30 patients, in before treatment and after treatment 2 weeks and 4 weeks, 8 weeks, 12 weekend by the self-assessment lists of symptom （SCL- 90） each factor and 12 weekend Hamilton depression scale （HAMD） reducing fraction evaluation curative effect, adverse reaction symptoms scale （Tess） to evaluate adverse drug reaction. [ Results ] Treatment 2 weeks and 4 weeks, 8 weeks, 12 weekend, the team of somatization, depression, anxiety and other factor points comparing with control group there were significant differences （P 〈 0.05）, the team＇s significant efficiency efficient is better than control group, all have significant difference （P 〈 0.05）, two groups of fewer side effects and relatively minor. [ ConcLusions ] Cognitive behavior therapy in combination with duloxetine treatment of depression somatization symptoms curative effect is better than the simple drug therapy.