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床边血液树脂灌流治疗重症急性胰腺炎28例临床观察

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摘要 目的观察血液树脂灌流治疗重症急性胰腺炎的临床疗效。方法对确诊为重症急性胰腺炎的28例患者,给予常规治疗的基础上,给予血液树脂灌流治疗,观察患者治疗前后的临床症状及血压、心率、呼吸等生命体征,监测丙氨酸氨基转氨酶(ALT)及天门冬氨酸氨基转氨酶(AST)、血脂、白介素-1(IL-1)、白介素-8(IL-8)、肿瘤坏死因子(TNF-α)、C反应蛋白(CRP)等指标。结果血液树脂灌流治疗重症急性胰腺炎临床效果明显,临床症状显著改善,血液灌流结束后,血AST、ALT、胆固醇、甘油三酯、IL-1、IL-8、TNF-α、CRP均有明显降低,差异具有显著意义(P<0.05),未发现明显不良反应。结论血液树脂灌能清除重症急性胰腺炎患者体内的炎症细胞因子、炎症介质,改善内环境及微循环,降低病死率,改善预后。
作者 刘克强
出处 《临床和实验医学杂志》 2012年第23期1894-1895,共2页 Journal of Clinical and Experimental Medicine
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