新疆哈萨克族人群易栓症危险性因素分析

Study on risk factors of thrombophilia in Hazakh population of XinJiang

目的分析新疆哈萨克族人群易栓症的危险性因素。方法调查398例新疆阿勒泰地区正常人群,检测蛋白C、蛋白S以及活化蛋白C抵抗,将检测结果超出正常42例分为病例组,其余356例分为对照组。对可能影响易栓症形成的因素进行单因素分析和logistic回归模型分析。结果在logistic回归模型分析结果显示性别、年龄、高血压、体质量、吸烟、喝酒并不是哈萨克族人群易栓症的危险因素。结论本次研究中性别、年龄、高血压、体质量、吸烟、喝酒等常见危险因素与哈萨克族人群易栓症发生并无明显关系。受制于此次调查的样本例数,更加确切的流行病学证据还有待于进一步扩大样本量后进行调查分析论证。

Objective To analyze the risk tactom of thrombophilia in Hazakh population in Xinjiang. Methods A total of 398 health a- dults in Altay Area of XinJiang, they were divided into two groups by results of detection of protein C, protein S and active protein C resistence. There were 42 cases in thrombophilia group and 356 cases in control group. Results In this study with logistic regression analysis, age, gender, hypertension, smoking and alcohol drinking had no correlation with thrombophilia, hence these were not risk factors of thrombophilia. Conclusion Age, gender, hypertension, smoking and alcohol drinking had no correlation with thrombophilia. However, due to the limitation of amount of cases, the evidence of epidemiology still needs further study with larger amount of samples.