体检人群高尿酸血症患病情况及相关因素分析

Analysis of correlation factors and prevalence of hyperuricemia in physical examination population

目的了解高尿酸血症（HUA）在不同年龄、不同性别体检人群中的患病情况,探讨血尿酸与年龄、体重指数、血压、血脂、血糖的相关性。方法通过对415例年龄24~87岁体检人群的检查结果进行总结,分析比较HUA组与非HUA组各项指标差异,并将血尿酸水平与相关因素进行多元逐步回归分析。结果本次调查HUA患病率为19.5%,老年组患病率最高为27.2%,男性患病率高于女性;HUA组年龄、体重指数、血压、血糖、三酰甘油水平均高于非HUA组,高密度脂蛋白胆固醇水平低于非HUA组（P〈0.05）。对相关因素进行多元逐步回归分析,最后进入回归方程的变量为体重指数、高密度脂蛋白胆固醇、收缩压、三酰甘油（P〈0.05）。结论 HUA具有较高患病率,与年龄、性别、肥胖、血压、血糖、血脂关系密切,HUA患者应注意合理饮食,控制体重,监测血压。

Objective To study the prevalence of hyperuricemia（HUA） in different age and gender physical examination population,in order to investigate the relationship between serum uric acid and age,body mass index（BMI）,blood pressure,blood lipid,blood glucose（GLU）.Methods Through summing up the check results of 415 cases of physical examination population aged 24 to 87,several factors were analyzed and compared between HUA group and non-HUA group.Then serum uric acid level and related factors were given multivariate stepwise regression analysis.Results The prevalence of hyperuricemia in this survey was 19.5%,and the older group had the highest rate of 27.2%,the prevalence of male was higher than female.Age,BMI,blood pressure,GLU,triglycerides（TG） in HUA group were higher than those of non-HUA group,while HDL-C level was lower than that of non-HUA group（P〈0.05）.Then multivariate stepwise regression analysis was carried out,finally BMI,HDL-C,SBP,TG entered the regression equation.Conclusion HUA has high prevalence rate and it is closed to age,gender obesity,blood pressure GLU and blood lipid.HUA patients should pay attention to the reasonable diet,weight control and monitoring of blood pressure.