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贝那普利治疗充血性心力衰竭的疗效观察 被引量:2

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摘要 目的观察血管紧张素转换酶抑制剂(ACEI)贝那普利治疗充血性心力衰竭(CHF)的治疗效果。方法将104例CHF患者随机分成观察组和对照组,观察组70例患者在常规的"强心、利尿、扩血管"治疗基础上加用贝那普利,从小剂量开始逐步达到"靶剂量";对照组34例患者仅给予常规治疗(强心、利尿、扩血管)。疗程均为3个月,比较两组治疗前后心率、血压、左室收缩末期内径(LVESD)、左室舒张末内径(LVEDD)、左室射血分数(LVEF)指标的变化,并观察两组患者的治疗效果。结果观察组总有效率为91.4%,对照组总有效率为67.6%,两组患者疗效比较,差异有统计学意义(P<0.05)。治疗后两组患者心率、收缩压、舒张压、LVESD、LVEDD、LVEF比较,差异有统计学意义(P<0.05)。结论贝那普利治疗CHF可明显改善患者的临床症状及心功能,提高生存率和生活质量,防止和延缓心肌重塑的发展,从而降低CHF的病死率,值得在临床上推广使用。
出处 《实用心脑肺血管病杂志》 2012年第12期1979-1980,共2页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
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