摘要
目的分析肱踝脉搏波传导速度(baPWV)与多种临床因素之间的关系,探讨baPWV的影响因素。方法随机抽取2010年5月—2010年11月来我院健康管理中心体检的1 764例体检者,进行baPWV检测。按照所测baPWV值分成两组,<1 400 cm/s者为低baPWV组(n=1 144),≥1 400 cm/s者为高baPWV组(n=620)。以baPWV值为应变量,以年龄、体质指数(BMI)、收缩压(SBP)、舒张压(DBP)、平均动脉压(MAP)、空腹血糖、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、心率为自变量,进行相关分析及逐步回归分析。结果 (1)高baPWV组除HDL-C水平低于低baPWV组外,其余各指标水平均高于低baPWV组,差异有统计学意义(P<0.05)。(2)单因素相关分析显示,年龄、SBP、DBP、MAP、空腹血糖、心率与baPWV呈正相关(P<0.05)。(3)多元线性回归分析显示,年龄、SBP、心率是baPWV的影响因素(P=0.00)。回归方程:baPWV=-255.97+8.024×年龄+7.681×SBP+5.877×心率。结论 baPWV与多种心血管疾病的影响因素有关,年龄、SBP和心率是其主要影响因素。
Objective To study influencing factors of brachialankle pulse wave velocity and its relationship with the risk factors of cardiovscular disease.Methods Totally 1 764 healthy subjects who received health check-ups in our center from May 2010 to November 2010 were enrolled for baPWV measurement.Based on the results,these subjects were divided into low baPWV group（baPWV1 400 cm/s）and hig baPWV group（baPWV1 400 cm/s）.With the baPWV value as the dependent variable and age,body mass index（BMI）,systolic blood pressure（SBP）,diastolic blood pressure（DBP）,mean artery pressure（MAP）,fasting blood glucose（Glu）,blood cholesterol（TC）,blood glycerin（TG）,high density lipoprotein-cholesterol（HDL-C）,low density lipoprotein-cholesterol（LDL-C）,and heart rate（HR） as the independent variables,the correlations between baPWV and the risk factors of cardiovascular diseases were analyzed.Results The age,BMI,SBP,DBP,MAP,Glu,TC,TG,and LDL-C were significantly higher in the high baPWV group than in the low baPWV group（P0.05）.Univariate analysis showed that the age,SBP,DBP,MAP,GLU and HR was significantly correlated with baPWV（P0.05）.Multivariate Logistic regression analysis showed that age,SBP and HR were positively correlated with baPWV（P=0.00）.Conclusion baPWV can be a useful predictor of cardiovascular diseases.Age,SBP and HR are the main influential factors of baPWV.
出处
《中国全科医学》
CAS
CSCD
北大核心
2012年第32期3697-3699,共3页
Chinese General Practice
