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晚期糖基化终产物及受体与动脉粥样硬化的研究进展 被引量:2

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摘要 动脉粥样硬化(atherosclerosis,AS)是一种多因性疾病。目前,尽管AS的诊断与治疗有了长足的进步,但对其病因学的认识仍然不足。近年来的基础研究及临床研究结果提示,在AS的不同临床表现形式中,晚期糖基化终产物(AGEs)参与其发生、发展的不同环节[1],而晚期糖基化终末产物受体(RAGE)是一种模式识别受体,它与多种内源性配体相互作用,引起一系列细胞信号事件。
出处 《南昌大学学报(医学版)》 CAS 2012年第10期97-99,106,共4页 Journal of Nanchang University:Medical Sciences
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  • 1李碧慧,林少达.可溶性晚期糖基化终产物受体与糖尿病慢性并发症[J].中华临床医师杂志(电子版),2011,5(16):4802-4804. 被引量:4
  • 2王瑞良,苏青.RAGE及其配体的临床意义研究进展[J].国际内分泌代谢杂志,2006,26(3):160-162. 被引量:23
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