地佐辛在妇科腹腔镜手术后镇痛效果的观察体会

The experience of dezocine for postoperative pain of laparoscopic gynecological surgeries

目的：观察妇科腹腔镜手术中不同时段应用地佐辛的术后镇痛效果。方法：将72例ASA分级Ⅰ~Ⅱ级的妇科腹腔镜手术患者采用随机数字表法分为两组（n=36）,A组于手术切皮前15 min静注地佐辛10 mg,B组于手术结束前15 min静注地佐辛10 mg,分别于术后2 h、4 h、8 h、12 h、24 h记录视觉模拟评分（visual analog scales,VAS）、副作用发生情况。结果：A组患者术后各时点VAS评分低于同时点B组（P〈0.05）,两组患者不良反应发生率差异无统计学意义（P〉0.05）。结论：地佐辛术前镇痛可有效减轻妇科腹腔镜手术患者的术后疼痛,且不增加术后副作用发生率。

Objective：To observe the postoperative analgesic effect of dezocine applied in different time.Methods：Seventy-two patients（by ASA I-II） who underwent laparoscopic gynecological surgeries were randomly divided into group A（n=36） and group B（n=36）.In group A,10 mg dezocine was intravenously injected 15 min before the operation,and the same dose was used 15 min before the end of the surgery.Visual analog scales（VAS） and the side effects were recorded at 2 h,4 h,8 h,12 h,24 h postoperatively.Results：VAS were lower in group A than than in group B at the respective time（P0.05）.There was no significant difference in side effects between groups（P0.05）.Conclusions：Dezocine applied preoperatively could effectively relieve postoperative pain after laparoscopic gynecological surgeries and does not increase the side effects.