宫颈液基细胞学33417例年龄分组统计结果分析

Statistics analysis of women′s cervical liquid-based cytology test

目的探讨妇科液基细胞学结果与年龄分组的相关关系。方法将2006年11月至2012年2月33 417例在北京市石景山医院妇科门诊做妇科液基细胞学检查患者按年龄分组,统计宫颈上皮异常发病率在各年龄组分布的特点。结果育龄妇女的发病率为8.52%,而非育龄妇女的发病率为6.37%;育龄妇女各年龄组不典型性鳞状细胞(ASC)和不典型腺细胞(AGC)发病率差异无统计学意义(P>0.05),40～49岁组开始轻度下降,但低度鳞状上皮内病变(LSIL)和高度鳞状上皮内病变(HSIL)反而开始升高,癌变发生率最高;非育龄妇女50～59岁年龄组的阳性率为5.87%,有所下降,但仍有各种病变发生;60～69岁和70～79岁组ASC仍然出现,但却没有更严重的病变,为安全期年龄组。结论超薄液基细胞学检查对20～50岁年龄组都有价值,但对60岁以上年龄组价值不大。

Objective To study the correlation of cervical Thinprep cytologic test（TCT） results and the age distribution. Methods The 33 417 cases of cervical Thinprep cytologic test in department of gynecology from november 2006 to february 2012 were grouped by age in this study and diagnosed by TBS project. The correlation of cytological positive cases and their age of onset were analysed. Results （1） The incidence of reproductive women was 8.52% and that of non-reproductive women was 6.37%. The incidence of ASC and AGC was similar in each age stage for reproductive women, although that in 40-49 years old women was descended slightly. However, in this group, the incidence of LSIL and HSIL began to step up, and that of carcinoma was the highest. The incidence rate of positive cases（5.87 % ） in 50-59 years old women was descended, but various kinds of pathological changes were re- main founded. ASC in 60 and 70 age stages was still founded, but more serious pathological change wasnlt founded. Those age stages were safe. Conclusion The TCT technique can have satisfactory applicability for screening cervical pathological changes in 20-50 age stage, but has＇t in 60 age stage.