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4项指标含量水平变化在2型糖尿病微血管病变中的相关性分析 被引量:2

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摘要 目的探讨血小板计数(PTL)、同型半胱氨酸(Hcy)、尿微量白蛋白(U-mAlb)、糖化血红蛋白(HbAlc)的含量水平变化与2型糖尿病微血管病变的关系。方法测定152例2型糖尿病患者PLT、血小板平均体积(MPV)、血小板分布宽度(PDW)、血清Hcy、U-mAlb及HbAlc含量,并将结果与90例健康对照组相同指标检测结果做统计学分析。结果 2型糖尿病组的HbAlc、PLT、MPV、PDW、Hcy、U-mAlb的浓度显著高于健康对照组,差异有统计学意义(P<0.05)。2型糖尿病组中,U-mAlb水平随HbAlc的增高而增高,二者呈明显正相关(P<0.05),2项指标各相邻组间的差异具有统计学意义(P<0.05)。HbAlc水平增高,PLT、MPV、PDW、Hcy水平随之增高,呈显著正相关(P<0.05)。结论联合检测PTL、Hcy、U-mAlb、HbA1c对2型糖尿病微血管病变的早期预防诊断及治疗有重要意义。
作者 王菡 刘建强
出处 《检验医学与临床》 CAS 2012年第23期2976-2978,共3页 Laboratory Medicine and Clinic
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