小儿轮状病毒性肠炎与血清转氨酶及心肌酶水平的相关性分析

Analysis on the correlation between pediatric rotavirus enteritis and serum levels of transaminases and myocardial enzymes

目的:探讨小儿轮状病毒(RV)性肠炎与血清转氨酶和心肌酶谱变化的关系。方法:对2010～2011年收治的62例小儿RV性肠炎(观察组)和RV抗原阴性的57例肠炎患儿(对照组)进行血清转氨酶及心肌酶谱测定,对其结果进行对比分析。结果:观察组血清转氨酶明显高于对照组,且年龄越小肝功异常率越高;观察组患儿心肌酶谱各指标明显高于对照组,差异有统计学意义(P<0.05)。结论:小儿RV性肠炎可引起血清心肌酶谱和转氨酶异常;早期监测血清转氨酶和心肌酶谱变化,对小儿RV性肠炎的诊断和干预治疗有重要参考意义。

Objective： To explore the relationship between pediatric rotavirus enteritis and changes of serum transaminases and myocardial enzymes levels. Methods： The serum levels of transaminases and myocardial enzymes in 62 infants with pediatric rotavirus enteritis （ observation group） and 57 infants with enteritis and negative rotavirus antigen （ control group） who were treated in the hospital from 2010 to 2011 were detected, then the results in the two groups were compared and analyzed. Results： The serum levels of transaminases in observation group were statistically significantly higher than those in control group, and the younger the infants were, the higher the incidence of abnormal liver function was ; the serum level of myocardial enzymes in observation group were statistically significantly higher than those in control group （ P 〈 0. 05 ） . Conclusion： Pediatric rotavirus enteritis can induce abnormal serum myocardial enzymes and transaminases ; moni- toring the changes of serum transaminases and myocardial enzymes early has important referential meaning for diagnosis, intervention, and treatment of pediatric rotavirus enteritis.