空腹血糖水平与急性冠脉综合征患者预后的相关性研究

Relationship between fasting plasma glucose and acute coronary syndrome

目的探讨空腹血糖(FPG)水平与急性冠脉综合征(ACS)患者预后的相关性。方法依据患者入院次日的FPG水平将386例ACS患者分为3组:A组112例,FPG2.8～6.9mmol/L;B组178例,FPG7.0～11.09mmol/L;C组96例,FPG>11.1mmol/L。对3组住院期间恶性心血管事件的发生情况进行比较。结果 B组严重心律失常、心力衰竭发生率与A组比较,差异有统计学意义(P<0.05或P<0.01),但两组心源性休克和心源性猝死发生率比较,差异无统计学意义(P>0.05)。C组所有恶性心血管事件发生率与A组和B组比较,差异均有统计学意义(P<0.05或P<0.01)。结论 ACS患者的FPG水平与近期预后密切相关,应加强对ACS患者的血糖监测及有效控制。

Objective To explore the relationship between fasting plasma glucose（FPG） level and the prognosis of patients with acute coronary syndrome（ACS）. Methods Three hundred and eighty six ACS patients were divided into A group（n = 112, FPG 2.8-6.9mmol/L）, B group （n = 112, FPG 7.0-11.09 mmol/L） and C group （n = 96, FPG11.1mmol/L） according to the FPG of the second day after admission. The incidence of adverse cardiovascular events during hospitalization were compared among three groups. Results The incidence of severe cardiac arrhythmia and heart failure in B group were higher than those of A group（P 0.05 or P 0.01）, but there were not statistical differences in the incidence of cardiogenic shock and sudden cardiac death between both groups（both P 0.05）. The incidences of all adverse cardiovascular events in C group were significantly higher than those of A group or B group （P 0.05 or P 0.01）. Conclusion The FPG level of ACS patients is related to the recent prognosis, and special attention should be paid on monitoring and controlling the blood glucose.