重症急性胰腺炎早期非手术治疗48例临床分析

Clinical analysis of non-surgical treatment for early stage of severe acute pancreatitis in 48 cases

目的探讨重症急性胰腺炎的合理治疗方案。方法以1995年1月～2011年12月本院收治的48例重症急性胰腺炎患者作研究对象,比较手术组与非手术组的主要并发症发生率和死亡率。A组:1995年1月～2003年12月以手术治疗为主22例;B组:2004年1月～2011年12月以早期非手术治疗为主26例。结果手术组死亡率和并发症明显高于非手术组,两组死亡率及并发症发生率比较,差异有统计学意义(P<0.05)。结论重症急性胰腺炎采用早期非手术治疗能有效降低死亡率和并发症发生率。大多数重症急性胰腺炎患者可经非手术治愈。

Objective To discuss the reasonable therapeutic schedule of severe acute pancreatitis. Methods Forty eight cases of patients with severe acute pancreatitis treated in our hospital from January 1995 to December 2011 were selected as the research objects. The incidence of main complications and mortality between the surgical group and non-surgical group were compared. 22 cases of patients who were given operative treatment from January 1995 to December 2003 were selected as the surgical group; 26 cases of patients who were given early non-surgical treatment from January 2004 to December 2011 were selected as the non-surgical group. Results The mortality and complications of the surgical group were higher than those of the non-surgical group, the differences were statistically significant （P 0.05）. Conclusion Early non-surgical treatment for severe acute pancreatitis can reduce the mortality and incidence of complications effectively. Most severe acute pancreatitis patients can be cured by non-surgical.