奥曲肽注射液治疗肝硬化合并上消化道出血临床疗效分析

Clinical effect analysis of octreotide injection in treatment of cirrhosis with upper gastrointestinal bleeding

目的观察奥曲肽注射液治疗肝硬化合并上消化道出血患者的临床疗效。方法将本院2008～2012年收治的80例肝硬化合并上消化道出血的患者,随机分为对照组和实验组。对照组40例,均采用垂体后叶素止血,实验组40例,均采用奥曲肽注射液止血。结果实验组止血时间、48h再出血率和不良反应发生率均低于对照组,差异有统计学意义(P<0.05)。实验组总有效率大于对照组,差异有统计学意义(P<0.05)。结论采用奥曲肽治疗肝硬化上消化道出血,止血迅速,不易复发,不良反应少,临床疗效显著,值得在临床上推广。

Objective To observe the effect of octreotide injection in treatment of patients with cirrhosis with upper gastrointestinal bleeding. Methods During 2008 to 2012, 80 cases were selected and divided into two groups. Control group included 40 cases used pituitary vasopressin and test group included 40 cases used octreotide injection. Results The hemostatic time, rebleeding rates and adverse reactions of test group were lower than that of control group, the differences were statistically significant （P 0.05）. The total efficiency of test group was higher than that of the control group, the difference was statistically significant （P 0.05）. Conclusion Using octreotide injection in treatment of patients with cirrhosis with upper gastrointestinal bleeding can stop bleeding fast and has fewer recurrence and adverse reactions. It has a significant clinical effect so that can be popularized.