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食管癌的分子靶向治疗研究进展

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摘要 近年来,手术及放射、化学疗法在食管癌治疗方面取得了一定的进步,然而对食管癌患者并没有带来长期生存率的明显增高。分子靶向治疗在食管癌的应用逐渐受到越来越多的关注。目前,已有众多Ⅰ/Ⅱ期临床试验用于评估食管癌分子靶向治疗疗效。
作者 鲜爽 彭枫
出处 《华西医学》 CAS 2012年第11期1751-1753,共3页 West China Medical Journal
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  • 1Jemal A, Bray F, Center MM, et al. Global cancer statistics[J]. CA Cancer J Clin, 2011, 61(2): 69-90.
  • 2Kim T, Grobmyer SR, Smith R, et al. Esophageal cancer: the five year survivors[J]. J Surg Oncol, 2011, 103(2): 179-183.
  • 3孙晓江,许亚萍(综述),毛伟敏(审校).表皮生长因子受体靶向抑制剂在食管癌中的应用[J].国际肿瘤学杂志,2010,37(12):922-925. 被引量:4
  • 4Liu QW, Fu JH, Luo KJ, et al. Identification of EGFR and KRAS mutations in Chinese patients with esophageal squamous cell carcinoma[J]. Dis Esophgus, 2011, 24(5): 374-380.
  • 5Safran H, Suntharalingam M, Dipetrillo T, et al. Cetuximab with concurrent chemoradiation for esophagogastric cancer: assessment of toxicity[J]. Int J Radiat Oncol Biol Phys, 2008, 70(2): 391-395.
  • 6Lorenzen S, Schuster T, Porschen R, et al. Cetuximab plus cisplatin-5-fluorouracil versus cisplatin-5-fluorouracil alone in first-line metastatic squamous cell carcinoma of the esophagus: a randomized phase II study of the Arbeitsgemeinschaft Intemistische Onkologie[J]. Ann Oncol, 2009, 20(10): 1667-1673.
  • 7Ruhstaller T, Pless M, Dietrich D, et al. Cetuximab in combination with chemoradiotherapy before surgery in patients with resectable, locally advanced esophageal carcinoma: a prospective, multicenter phase I B/ II Trial (SAKK 75/06) [J]. J Clin Oncol, 2011, 29(6): 626-631.
  • 8Gold P J, Goldman B, Iqbal S, et al. Cetuximab as second-line therapy in patients with metastatic esophageal adenocarcinoma: a phase II Southwest Oncology Group Study (S0415)[J]. J Thorac Oncol, 2010, 5(9): 1472-1476.
  • 9Chan JA, Blaszkowsky LS, Enzinger PC, et al. A multicenter phase II trial of single agent eetuximab in advanced esophageal and gastric adenocarcinoma[J]. Ann Oncol, 2011, 22(6): 1367-1373.
  • 10Rodriguez CP, Adelstein D J, Rice TW, et al. A phase II study of perioperative concurrent chemoradiotherapy, gefitinib in locoregionally advanced esophagus and gastroesophageal junction cancer[J]. J Thorac Oncol, 2010, 5(2): 229-235.

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