不同剂量谷胱甘肽对老年髋关节置换手术患者血浆心肌肌钙蛋白Ⅰ水平的影响

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摘要对择期行髋关节置换手术老年患者，经颈内静脉输注不同剂量谷胱甘肽，观察术前及骨水泥置入后12h内血浆心肌肌钙蛋白Ⅰ水平变化。结果显示，谷胱甘肽可呈剂量依赖性的减轻髋关节置换手术老年患者心肌损伤。

作者刘海林张阳钱燕宁

出处《中华全科医师杂志》 2012年第12期949-950,共2页 Chinese Journal of General Practitioners

关键词谷胱甘肽

参考文献5

1李远强,宫本晶,王志刚.还原型谷胱甘肽预先给药对体外循环心脏直视手术患儿心肌损伤的影响[J].中华麻醉学杂志,2010,30(4):506-507. 被引量：3
2Fuchs F, Grabarek Z. The Ca^2+/Mg^2+ sites of troponin C modulate crossbridge-mediated thin filament activation in cardiac myofibrils. Biochem Biophys Res Commun,2011,408:697-700.
3Kim K J, Chen DG, Chung N, et al. Direct myocardial depressant effect of methylmethacrylate monomer: mechanical and electro- physiologic actions in vitro. Anesthesiology,2003,98 : 1186-1194.
4Ghanta S, Chattopadhyay S. Glutathione as a signaling molecule: another challenge to pathogens. Plant Signal Behav, 2011,6:783- 788.
5Ramires PR, Ji LL. Glutathione supplementation and training increases myocardial resistance to ischemia-reperfusion in vivo. Am J Physiol Heart Circ Physiol,2001,281 :H679-688.

1赵丽丽,王一彪,朱晓波,张兆华.还原型谷胱甘肽对缺氧/复氧培养大鼠心肌细胞的干预性研究[J].山东大学学报（医学版）,2005,43(11):1049-1051. 被引量：3
2夏世文,王惠,张漪.还原型谷胱甘肽治疗新生儿缺氧缺血性心肌损害的疗效观察[J].中国当代儿科杂志,2006,8(4):341-342. 被引量：6
3Leichtweis S,Leeuwenburgh C,Bejma J,et al.Aged rat hearts are not more susceptible to ischemia-reperfusion injury in vivo:role of glutathione.Mech Ageing Dev,2001,122(6):503-518.
4Leichtweis S,Ji LL.Glutathione deficiency intensifies ischaemiare-perfusion induced cardiac dysfunction and oxidative stress.Acta Phyaol Scand,2001,172(1):1-10.
5Ramires PR,Ji LL.Glutathione supplementation and training increases myocardial resistance to ischemia-reperfusion in vivo.Am J Physiol Heart Circ Physiol,2001,281(2):H679-H688.
6袁媛,高国栋,龙村.还原型谷胱甘肽含血停搏液在心脏瓣膜置换术中的心肌保护作用[J].中国循环杂志,2008,23(1):50-52. 被引量：7

中华全科医师杂志

2012年第12期

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