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浅谈优化抗生素治疗的相关问题 被引量:5

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摘要 抗生素合理应用作为抗菌治疗的基本原则,虽然一直反复被强调.但是总体上并未收到预期的效果.抗生素应用混乱和滥用现象仍然十分严重。抗生素不合理应用,细菌耐药率上升、多药耐药和泛耐药菌株出现,呼唤人们寻找和研发新的抗生素。但由于新药研发难度大.投入风险高。近年来国际上新抗生素研发的步伐滞后于耐药的增加。目前我们所面临的窘境就是细菌耐药使抗生素失去作用,但细菌性感染仍在肆虐,迫切需要有效治疗,研发新抗生素又相对滞后,就使得人们越来越关注如何更好地使用现有的药物,延长他们的临床寿命,减少或减缓耐药菌的出现。
出处 《中国药物与临床》 CAS 2012年第12期1525-1528,共4页 Chinese Remedies & Clinics
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