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针对缺氧诱导因子-1α的靶向治疗增加前列腺癌PC3细胞的放射敏感性 被引量：1

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摘要 缺氧会降低前列腺癌（Pca）放疗效果，该过程可能是通过缺氧诱导因子-1α（HIF-1α）介导的，降低HIF-1α表达可能有放疗增敏作用。我们沉默前列腺癌PC3细胞的HIF-1α基因，观察其放射增敏作用。
作者 俞江 黄玉华 严春寅 侯建全 浦金贤 李纲 张光波 徐晓婷 付振宇 王锡智
机构地区 上海交通大学苏州九龙医院泌尿外科 苏州大学附属第一医院泌尿外科 苏州大学医学部免疫学实验室 苏州大学附属第一医院放疗科 常熟市第二人民医院泌尿外科
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2012年第12期2380-2380,共1页 Chinese Journal of Experimental Surgery
关键词 缺氧诱导因子-1Α PC3细胞 前列腺癌 放射敏感性 靶向治疗 HIF-1Α基因 放疗增敏作用 放射增敏作用
分类号 R737.25 [医药卫生—肿瘤]
  • 相关文献

参考文献4

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共引文献13

同被引文献13

  • 1赵维,付彤,刘国津,张凌.微血管密度和血管内皮因子在肺癌组织中的表达及临床意义[J].吉林大学学报（医学版）,2005,31(4):595-597. 被引量：6
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中华实验外科杂志
2012年 第12期

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