鼻腔上皮-肌上皮癌1例报告并文献复习

Epithelial-myoepithelial carcinoma arising in the nasal cavity: a case report and literature review

目的:探讨鼻腔上皮-肌上皮癌的病理学特点、诊断、治疗及预后。方法:对1例鼻腔上皮-肌上皮癌进行分析,光镜观察和免疫组织化学检查,并进行文献复习。结果:临床表现不具备特征性,诊断只能依靠病理检查。肿瘤主要由肌上皮细胞和腺上皮细胞等组成,免疫组织化学检测CK-L、CK-P、S-100、α-平滑肌肌动蛋白等表达阳性。结论:鼻腔上皮-肌上皮癌是一种罕见肿瘤,以手术治疗为主,有复发和远处转移的潜能。

Objective：To seek pathological features,diagnosis,treatment,prognosis of Epithelial-myoepithelial carcinoma arising in the nasal cavity.Method：One case of Epithelial-myoepithelial carcinoma arising in the nasal cavity was analyzed retrospectivelyand studied with immunohistochemical Staining and light microscopy,as well as review of the literature.Result：The clinicalfeature of epithelial-myoepithelial carcinoma in the nasal cavity was atypical and diagnosis relied on pathologic features.Epithelial-myoepithelial carcinoma consisted of myoepithelial and epithelial cells.Immunohistochemical staining demonstrated that cytokeratin P,cytokeratin L,S-100 protein,a-smooth muscle actin expressed positively.Conclusion：Epithelial-myoepithelial carcinoma in the nasal cavity is a rare neoplasm.Wide surgical excision with a clear margin is the main therapy,and these tumors have the potential for metastasis andrecurrence.