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白细胞介素-17在特发性胎儿生长受限胎盘组织中的表达及意义

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摘要 胎儿生长受限(FGR)是产科常见并发症之一,其围产儿死亡率为正常儿的4~6倍,是当代产科学的重要研究课题。某些FGR是由病理妊娠、妊娠合并症、胎盘功能减退、营养不良、遗传因素等引起,但约有40%的FGR发病原因不明,称为特发性胎儿生长受限(idiopathic fetal growth restriction,IFGR)E13。近年越来越多的学者认识到,免疫及感染因素在IFGR的发病机制中起着不可忽视的作用。研究表明,白细胞介素-17(Interleukin-17,IL-17)与妊娠免疫调节及炎症发展有关。本研究通过检测IL-17在IFGR患者胎盘组织中的表达情况,初步探讨IL-17与IFGR的关系。
出处 《生殖医学杂志》 CAS 2012年第6期593-595,共3页 Journal of Reproductive Medicine
基金 浙江省人口和计划生育科技项目 余姚市科技计划项目(2010Y02)
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