角膜屈光手术医师应注意抗炎类滴眼液对术后角膜生物力学的影响

Paying attention to the impact of anti-inflammatory eye drops on corneal biomechanical parameters

伴随科学技术的进步，角膜屈光手术疗效得到了不断的提高，人们在改善患者视觉质量的同时，也关注到角膜屈光手术后角膜生物力学改变带来的影响。角膜生物力学相关参数不但受角膜屈光手术的直接影响，同时也受到人体生理周期以及术后一些药物的影响，而这些影响是导致部分手术疗效不“稳定”的重要因素。手术对角膜生物力学的影响已受到了较多的关注，但对于术后部分抗炎类滴眼液的应用可能引发眼压升高、屈光回退、甚至视觉质量下降等了解尚不够。本文对抗炎类滴眼液在角膜屈光手术后局部应用的作用及其不良反应进行阐述，特别是角膜屈光手术后角膜生物力学变化的特点，以及部分抗炎类滴眼液应用后眼压升高对术后角膜生物力学进一步的影响进行讨论，提出了角膜屈光手术医师应加强抗炎类滴眼液对术后角膜生物力学潜在影响的重视。

Corneal refractive surgery continues to develop accompanied by a rapid advance in scientific knowledge and technology. Improvement in visual quality after corneal refractive surgery is an issue of increasing concerns. Furthermore, corneal biomeehanical alteration after corneal refractive surgery is a new problem. Corneal biomechanical parameters vary upon not only the quality of refractive surgery,but also the human physiological cycles and application of some postoperative drugs. These effects are sometimes very important factors for ＇ unstable ＇ outcomes. At present, much attention has been focused on the change of corneal biomechanics after operation,but the event of postoperative application of anti-inflammatory eye drops leading to ocular hypertension, refractive regression, even visual quality decline is still not well understood. Herein, the therapeutic effects and adverse responses of topical anti-inflammatory eye drops,especially the change in characteristics of corneal biomeehanics after corneal refractive surgery, as well as the application of topical anti-inflammatory eye drops were discussed. It is essential that corneal refractive surgeons should fully understand the potential impact of anti-inflammatory eye drops on corneal biomeehanics after corneal refractive surgery.