酒石酸布托啡诺复合丙泊酚麻醉用于门诊Leep刀宫颈锥切术的临床观察

The cilnical effect of butorphanol and propofol combined anesthesia in outpatient treated with Leep procedure

目的:观察酒石酸布托啡诺复合丙泊酚麻醉用于门诊Leep刀宫颈锥切术的临床效果。方法:选择临床诊断为"宫颈不典型增生Ⅱ-Ⅲ级"需进行Leep刀宫颈锥切术的患者共60例。随机分为两组:A组采用单纯丙泊酚麻醉;B组采用酒石酸布托啡诺复合丙泊酚麻醉。对其麻醉效果及不良反应等进行观察比较。监测MAP、HR、SpO2等指标。记录术中丙泊酚用量及术毕苏醒时间,术后15分钟疼痛评分等情况。结果:苏醒时间A组比B组延长,有统计学差异。术中与术前MAP比较,两组均有统计学差异。术中与术前HR、SpO2比较,A组有统计学差异,B组无统计学差异。术中MAP、HR、SpO2等指标两组比较有统计学差异。术后疼痛评分B组小于A组,有统计学差异。丙泊酚用量B组比A组也明显减少,两组比较有统计学差异。两组均无明显不良反应。结论:酒石酸布托啡诺复合丙泊酚麻醉用于门诊Leep刀宫颈锥切术,具有起效迅速、麻醉效果好、术后清醒快、不良反应少、术后镇痛良好等特点,是一种比较理想的麻醉方法,临床应用安全有效。

Objective：To observe the clinical effect of butorphanol and propofol using for Leep procedure on cervical intraepithelial neoplasia.Methods：Sixty patients treated with Leep for CINⅡ-Ⅲ were randomly divided into two groups：A group with a simple anesthesia propofol;group B,butorphanol and propofol anesthesia.The anesthetic effects and adverse reactions were observed and compared.monitoring MAP,HR,SpO2 and other indicators,record the amount of intraoperative propofol and recovery time of surgery,postoperative pain score.Results： The recovery time in group A was longer than that of in group B.MAP,HR,SpO2 and were significantly different in group B than that of in group A.Postoperative pain score was significantly lower in group B than that of in group A.Propofol dosage was significantly less in group B than that of in group A.Conclusion：Butorphanol and propofol combination anesthesia could be used for Leep procedure safely.