密毛番荔枝化学成分的研究

Chemical Constituents of Annona densicoma Mart.

采用正相、反相硅胶,Sephadex LH-20凝胶,MCI树脂等层析方法对密毛番荔枝茎枝的化学成分进行分离纯化,运用现代波谱技术鉴定了9个化合物:槲皮素(1),圣草酚(2),原儿茶酸(3),丁香酸(4),N-p-hydroxy-cis-coumaroyltyramine(5),annonacin(6),annonacin-10-one(7),β-谷甾醇(8)和胡萝卜苷(9)。其中化合物3为首次从该属植物中分离得到,化合物1、2、4、5、8和9均为首次从该植物中分离得到。

Nine compounds were isolated and purified from the stem of Annona densicoma Mart. by silica gel, reverse phase C18 silica gel, Sephadex LH-20, and MCI column chromatography, and their structures were elucidated as quercetin （ 1 ）, eriodietyol （ 2 ）, protocatechuic acid （ 3 ）, syringic acid （4）, N-p-hydroxy-cis-coumaroyltyramine （ 5 ）, annonacin （6） ,annonacin-10-one （7） ,β-sitosterol （8） and daucosterol （9） by modern spectroscopic methods. This was the first report of the isolation of 3 from genus Annona, and 1,2,4,5,8 and 9 were isolated from this plant for the first time.