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东亚五味子的木脂素类化学成分研究 被引量：2

Lignans from Schisandra elongata(BI.)Baill.
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摘要 目的研究产自陕西秦岭的东亚五味子茎叶的木脂素类化学成分。方法丙酮提取,分别经石油醚、乙酸乙酯及正丁醇萃取,采用硅胶色谱和HPLC制备色谱分离、纯化化学成分,通过波谱数据鉴定化合物结构。结果从产自陕西秦岭的东亚五味子茎叶中分离得到了8个木脂素化合物,分别鉴定为schizantherin B(1),tigloylgomisin P(2),gomisin G(3),gomisin M1(4),gomisin K3(5),epigomisin O(6),gomisin J(7),pre-gomisin(8)。结论以上化合物均为首次从东亚五味子中分离得到。 AIM To study the chemical compounds in Schisandra elongata（BI.） Baill..METHODS Chemical compounds were isolated by solvent-extraction（petroleum ether,ethyl acetate and n-butanol） together with column chromatography and their structures were determined by spectroscopic analysis.RESULTS Eight lignans were obtained and identified as schisantherin B（1）,tigloylgomisin P（2）,gomisin G（3）,gomisin M1（4）,gomisin K3（5）,epigomisin O（6）,gomisin J（7）,pre-gomisin（8）.CONCLUSION Those compounds are obtained from this plant for the first time.
作者 杨黎彬 黄胜雄 普建新 李丽梅 赵勇
机构地区 西安医学院药学院 中科院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室
出处 《中成药》 CAS CSCD 北大核心 2012年第12期2365-2368,共4页 Chinese Traditional Patent Medicine
关键词 东亚五味子 分离鉴定 木脂素 Schisandra elongata（BI.）Baill. isolate and identify lignan
分类号 R284.1 [医药卫生—中药学]
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参考文献12

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中成药
2012年 第12期

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