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腹膜透析与血液透析治疗儿童急性肾功能衰竭的疗效比较 被引量:3

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摘要 目的为探讨血液净化治疗儿童急性肾功能衰竭的效果,对我院进行的腹膜透析(peritoneal dialysis,PD)与血液透析(hemodialysis,HD)病例进行临床对比分析。方法回顾性分析我院1997年1月至2011年12月收治的急性。肾功能衰竭行血液净化治疗74例儿童的临床资料,其中PD45例,HD29例,分别比较腹膜透析组(PD组)与血液透析组(HD组)的疗效及并发症。PD组采用间歇性腹膜透析法,每天透析8次;HD组初次诱导透析,以后隔天透析1次。结果PD组尿毒症症状(纳差、恶心、呕吐、乏力)明显改善时间(5.6±2.3)d,HD组(3.2±1.7)d,差异有统计学意义(P〈0.05),HD组尿毒症症状改善快于PD组。透析1周后血生化指标尿素氮、肌酐、尿酸、HC03-与透析前比较差异无统计学意义(P〉0.05)。透析治疗时间上,HD组(10.4±2.5)d,PD组(11.2±3.6)d,差异无统计学意义(P〉0.05)。透析并发症方面,PD组总并发症20.0%,HD总并发症65.4%,HD组并发症多于PD组。结论PD与HD在治疗儿童急性。肾功能衰竭方面,改善尿毒症症状HD快于PD,但PD不良反应发生率低于HD,且PD操作简单、安全性高、费用低,可作为儿童急性。肾功能衰竭的首选净化方式。相对而言,HD起效快,对于急性肾功能衰竭、药物中毒及食物中毒等中毒性疾病则首选HD。
出处 《中国小儿急救医学》 CAS 2012年第6期625-627,共3页 Chinese Pediatric Emergency Medicine
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