大柴胡汤合保和丸治疗非酒精性脂肪性肝病的临床研究

Clinical Study of Dacaihu Decoction Plus Baohe Pill in Treating Nonalcoholic Fatty Liver Disease

目的:观察大柴胡汤合保和丸治疗非酒精性脂肪性肝病的临床疗效。方法:将60例非酒精性脂肪性肝病患者随机分为两组。治疗组30例,予大柴胡汤合保和丸口服治疗;对照组30例,予熊去氧胆酸口服治疗,疗程为3个月。观察临床疗效、肝功能、血脂和肝脏B超分级变化情况。结果:治疗组总有效率为86.67%,优于与对照组的70%(P<0.01);治疗组在改善肝功能、降低血脂水平和改善B超脂肪肝表现方面均优于对照组(P<0.05)。结论:大柴胡汤合保和丸治疗非酒精性脂肪性肝病具有较好的临床疗效。

Objective ： To observe the effect of Dacaihu Decoction plus Baohe Pill in treating nonalcoholic fatty liver dis ease（NAFLD）. Methods ：60 patients with NAFLD were randomly divided into two groups. 30 patients in treatment group were treated with Dacaihu Decoction plus Baohe Pill and 30 patients in control group with ursodeoxycholic acid. After 3 months, the therapeutic effect and liver function, TG, TC and liver ultrasound imaging were measured. Results ： The total ef fective rate in treatment group was 86.67 % and 70% in control group （P 〈 0.01 ）. Compared with the control group, the liver function and fatty liver ultrasound imaging were improved significantly,TG and TC were decreased significantly in the treatment group （ P 〈 0.05 ）. Conclusion ： Dacaihu Decoction plus Baohe Pill in treating NAFLD was proved effective.