期刊文献+

西妥昔单抗联合同步放化疗治疗食管癌的研究进展 被引量:3

下载PDF
导出
摘要 不断寻求能够提高疗效、降低毒性的有效药物是食管癌综合治疗追求的重要目标之一。与传统细胞毒性化疗药物相比,分子靶向药物以其靶点明确、特异性强、毒性小、安全性好,对转移瘤也有较好的疗效等特点,正成为肿瘤综合治疗研究的热点。近年来,分子靶向药物的研发为食管癌综合治疗提供了新的治疗途径。
出处 《肿瘤预防与治疗》 2012年第6期403-406,共4页 Journal of Cancer Control And Treatment
  • 相关文献

参考文献24

  • 1Syrigos KN,Zalonis A,Kotteas E,et al. Targeted therapy for oesophageal cancer : an overview [ J ]. Cancer Metastasis Rev, 2008,27 (2) :273-288.
  • 2Wang YN, Yamaguchi H, Hsu JM, et al. Nuclear trafficking of the epidermal growth factor receptor family membrane proteins [ J ]. Oncogene ,2010,29 (28) :3997-4006.
  • 3Ciardiello F, Tortora G. EGFR antagonists in cancer treatment [J]. N Engl J Med ,2008,358 ( 11 ) : 1160-1174.
  • 4Benvenuti S,Sartore-Bianchi A,Di Nicolantonio F,et al. Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies [J]. Cancer Res, 2007,15,67 (6) :2643-2648.
  • 5Lu H, Liang K, Lu Y, et al. The anti-EGFR antibody cetuximab sensitizes human head and neck squamous cell carcinoma cells to radiation in part through inhibiting radiation-induced upregulation of HIF-1α [J]. Cancer Lett, 2012,322( 1 ) :78-85.
  • 6Kurai J, Chikumi H, Hashimoto K, et al. Antibody dependent cellular cytotoxicity mediated by cetuximab against lung cancer cell lines [ J ]. Clin Cancer Res,2007,13 (5) : 1552-1561.
  • 7Boone J, Van HR, Offerhaus GJ, et al. Targets for molecular therapy in esophageal squamous cell carcinoma:an immunohistochemical analysis[J]. Dis Esophagus,2009,22(6) :496-504.
  • 8Wang KL, Wu Tr, Choi IS, el al. Expression of epidermal growth factor receptor in esophageal and esophagogastric junction adeno- carcinomas:association with poor outcome[J]. Cancer,2007,109 (4) :658-667.
  • 9Krause M,Schutze C,Petersen C, et al. Different classes of EGFR inhibitors may have different potential to improve local tumour control after fractionated irradiation: a study on C225 in FaDu hSCC [ J ]. Radiother Oncol,2005,74 ( 2 ) : 109-115.
  • 10Takaoka S, Lwase M, Uchida M, et al. Effect of combining epidermal growth factor receptor inhibitors and cisplatin on proliferation and apoptosis of oral squamous cell carcinoma cells [J]. Int J Oncol, 2007,30 ( 6 ) : 1469 - 1476.

同被引文献37

二级引证文献22

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部