微波法合成邻异丁烯氧基苯酚

Microwave-assisted Prepation of 2-Methallyloxyphenol

对在微波催化条件下邻苯二酚和氯代异丁烯单醚化反应进行了研究 ,考察了各种不同碱、相转移催化剂、溶剂、微波功率和反应时间对反应的影响。邻异丁烯氧基苯酚的收率由常规方法的 5 4%提高到 6 8% ,反应速率是常规方法的 1 2 0倍。

Methallyloxyphenol was prepared by the reaction of catechol with β-methallyl chloride in the presence of base and phase transfer catalyst under microwave irradiation. Under the optimum reaction condition the yield of the product was 68% and the reaction rate was 120 times as faster as that of the classical method.