穴位埋线治疗原发性男性乳房发育症临床观察

Clinical Observation on Acupoint Embedding in Treating Gynecomastia

目的观察穴位埋线治疗中青年原发性男性乳房发育症的疗效。方法将86例患者分为埋线组、中药组及西药组。观察3组总有效率,肿块大小、肿块硬度、乳房疼痛及全身伴随症状的治疗前后积分,及起效时间、消失时间,血清总睾酮(TTE)、雌二醇(E2)、泌乳素(PRL)水平。结果治疗1个疗程(12星期)后,3组总有效率比较差异无统计学意义(P>0.05),埋线组对于临床症状体征的改善、起效时间、消失时间较其他两组更有优势(P<0.01);E2水平较治疗前显著下降(P<0.01),TTE水平有所上升,但无统计学意义(P>0.05),PRL水平无明显变化(P>0.05)。结论穴位埋线治疗中青年原发性男性乳房发育症起效快,方便易行,无明显副反应,其可能通过下调体内雌雄激素比达到治疗效果。

Objective To observe the therapeutic efficacy of acupoint embedding therapy in treating primary gynecomastia in adolescents and middle-aged men. Method Eighty-six patients were divided into a thread-embedding group, a Chinese herbal medicine group, and a Western medicine group. The following items were observed in the three groups： total effective rate; scores of mass size and scirrhosity, breast pain, and general accompanied symptoms before and after treatment; effect set-up time and disappeared time; levels of total testosterone （TTE）, estrogen （E2）, and prolactin （PRL）. Result After a treatment course （12 weeks）, there were no significant differences in comparing the total effective rate among the three groups （P〉0.05）; thread-embedding group had obvious advantages in the improvement of clinical symptoms and signs, effect set-up time and disappeared time compared with the other two groups （P〈0.01）; the level of E2 dropped significantly （P〈0.01）, TTE rose without a statistical significance （P〉0.05）, and PRL level did not show obvious difference （P〉0.05）. Conclusion It is efficient, convenient, and free of side effects to use acupoint embedding therapy to treat primary gynecomastia in adolescents and middle-aged men, and it may realize its treatment effect by down-regulating the ratio between androgens and estrogens.