言语和语言障碍的行为遗传学研究

Behavior Genetic Studies on Speech and Language Disorders

言语和语言障碍是流行率很高的儿童交流障碍,迄今为止其发生机制尚不明确。行为遗传学研究显示常见的言语和语言障碍是多基因遗传疾病。近十年来分子遗传学研究已成为行为遗传学研究的主流,一系列言语和语言障碍相关基因座甚至基因得到鉴定,为研究言语和语言障碍的发生机制和治疗提供了可能。

Speech and language disorders are communication disorders for children with high prevalence, and the underlying causes are unclear until now. Behavior genetic studies show that language and speech disorders are muhifactorial inherited disorders. The development of the molecular genetic technology in the last decade enables the identification of speech and language disorders-associated gene loci even genes, which provides new perspective for the study of mechanism and treatment of speech and language disorders.