解脲脲支原体及沙眼衣原体感染与难免流产的关系分析

Relationship between Ureaplasma urealyticumand Chlamydia trachomatis infections and inevitable abortion

目的探讨解脲脲支原体(Uu)、沙眼衣原体(Ct)感染与难免流产的关系,以期降低和预防难免流产的发生。方法对65例难免流产者(观察组)和73例人工流产患者(对照组)采用PCR检测方法对宫颈分泌物分别进行Uu、Ct感染检测,并对两组检测结果进行统计分析。结果观察组宫颈分泌物Uu感染率为38.46%,对照组Uu感染率为10.96%,两组差异有统计学意义(P<0.01);观察组宫颈分泌物Ct感染率为29.23%,对照组Ct感染率为6.85%,差异有统计学意义(P<0.01);观察组宫颈分泌物Uu+Ct混合感染率为12.31%,对照组混合感染率为0,差异有统计学意义(P<0.01)。结论 Uu、Ct感染与难免流产有相关性,是引起难免流产的重要原因之一,孕前妇女进行Uu、Ct检测并积极治疗,对防止不良妊娠结局再次发生有重要意义。

OBJECTIVE To explore the correlation between the Chlamydia trachomatis（CT） infections,Ureaplasma urealyticum（UU） infections and inevitable abortion so as to reduce and prevent the incidence of inevitable abortion.METHODS PCR method was used to detect CT and UU in cervical secretions of 65 cases with inevitable abortion（the observation group） and 73 cases with artificial abortion（the control group）,and then the results were taken for statistical analysis.RESULTS The total detection rates of UU in the observation group and the control group were 38.46% and 10.96%,respectively,there was significant difference between the two groups（P0.01）.The total detection rates of CT in the observation group and the control group were 29.23% and 6.85%,respectively,there was significant difference between the two groups（P0.01）.The total detection rates of UU and CT in the observation group and the control group were 12.31% and 0%,respectively,there was significant difference between the two groups（P0.01）.CONCLUSION The CT infections and UU infections are related to the inevitable abortion,and they are the risk factors for the inevitable abortion.The detection of CT and UU before the pregnancy combined with active treatment plays an important role in prevention of reoccurrence of adverse pregnancy outcomes.