武汉市2001—2010年戊型肝炎流行病学分析

Prevalent features of hepatitis E among residents in Wuhan from 2001 to 2010

目的分析2001—2010年湖北省武汉市戊型肝炎(戊肝)的发病情况和变化趋势。方法采用描述性流行病学方法和线性相关分析。结果 2001—2010年武汉市报告戊肝5 011例,年均发病率为6.20/10万;戊肝发病率呈先升高后下降的趋势(χ2=836.53,P<0.001),但发病率仍维持在较高水平,戊肝常年散发,无明显的季节性,但冬春季发病相对较多;年均发病率中心城区高于远城区(χ2=1 284.65,P<0.001),戊肝发病率随着年龄增加呈上升趋势(r=0.816,P<0.001),55～84岁发病率较高,男性高于女性(χ2=848.01,P<0.001);在总病例中,离退休人员占28.46%,其次是工人占16.74%。结论近年武汉市戊肝发病率较高,中心城区是高发区,男性、离退休人员、>50岁中老年人是发病的重点人群。

Objective To analyze the incidence and epidemiological trend of hepatitis E（HE） among residents in Wuhan from 2001 to 2010.Methods Descriptive epidemiological and correlation analytical methods were used.Results Totally 5 011 cases of HE were reported in Wuhan from 2001 to 2010,with an average incidence of 6.20 per 100 000 and a downward trend（χ2=836.53,P0.001）.No obvious seasonal distribution was observed for the reported HE cases,but the incidence was relatively higher in winter and spring.The average incidence of HE was higher in the urban than in the rural（χ2=1 284.65,P0.001）.The incidence of HE increased with the increment of age（r=0.816,P0.001）and was the highest in the risidents aged 55 to 84 years,and higher in male than in female（χ2=848.01,P0.001）.Among the all cases,retirees accounted for 28.46 percent and workers were 16.74 percent.Conclusion In recent years,the incidence of HE was high among the residents in Wuhan city and was higher in urban residents,male population,retirees,and the people aged over fifty.