高效液相色谱法测定桂枝茯苓丸制剂及含药血清中芍药苷、肉桂酸、丹皮酚

Detection of Paeoniflorin、 Paeonol、Cinnamic Acid in Guizhifulingpill and Medicated Serum by HPLC

目的:对桂枝茯苓丸制剂及含药血清的指标性成分进行检测,为桂枝茯苓丸进一步深入研究奠定基础。方法:采用高效液相色谱法测定桂枝茯苓丸制剂及含药血清芍药苷、肉桂酸、丹皮酚。结果:桂枝茯苓丸制剂中三种成分均可检出,含药血清中检出肉桂酸、丹皮酚成分,未检出芍药苷成分。结论:采用高效液相色谱法可以检测出体内、体外桂枝茯苓丸制剂中的指标性成分,方法简单、可靠。

Objective：to establish the index components detection method of guizhifuling pill, and to lay a foundation of further study on it. Methods：verify paeoniflorin, paeonol,cinnamic acid in guizhifuling pill and medicated serum by HPLC. Results： pae oniflorin, paeonol,cinnamic acid in guizhifuling pill can be detected ; paeonol,cinnamic acid in medicated serum can be detected ,but paeoniflorin can＇t be detected in medicated serum Conclusion：index components in guizhifuling pill and medicated serum can be detected by HPLC, and the method is simple and reliable .